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Thomas G Parker Selected Research

omapatrilat

10/2005Vasopeptidase inhibition peri- and post-MI in Zucker insulin resistant rats: effect on MI size, arrhythmias, remodeling, function and fetal gene expression.
3/2005Effects of the vasopeptidase inhibitor omapatrilat on peri- and postmyocardial infarction in Zucker lean rats.
12/2003Comparative effects of a vasopeptidase inhibitor vs. an angiotensin converting enzyme inhibitor on cardiomyocyte apoptosis in rats with heart failure.

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Thomas G Parker Research Topics

Disease

11Myocardial Infarction
01/2017 - 01/2002
7Infarction (Infarctions)
01/2017 - 03/2005
6Fibrosis (Cirrhosis)
01/2017 - 01/2002
5Heart Failure
06/2012 - 05/2002
5Cicatrix (Scar)
02/2012 - 01/2002
4Sepsis (Septicemia)
10/2022 - 03/2010
4Schizophrenia (Dementia Praecox)
01/2022 - 01/2015
4Cardiomegaly (Heart Hypertrophy)
01/2017 - 03/2005
3Insulin Resistance
01/2018 - 03/2005
3Neoplasms (Cancer)
01/2015 - 09/2010
3Hypertrophy
03/2013 - 01/2002
2Parkinson Disease (Parkinson's Disease)
01/2022 - 06/2021
2Atrial Fibrillation
01/2021 - 01/2018
2Hypoxia (Hypoxemia)
01/2018 - 01/2017
2Ischemia
01/2017 - 04/2014
2Pulmonary Hypertension
01/2015 - 05/2013
2Hypertension (High Blood Pressure)
01/2015 - 11/2005
2Bipolar Disorder (Manic Depressive Psychosis)
01/2015 - 07/2014
2Right Ventricular Hypertrophy
05/2013 - 03/2005
1Infections
10/2022
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022
1Critical Illness (Critically Ill)
01/2021
1Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2021
1Type 2 Diabetes Mellitus (MODY)
11/2020
1Diabetes Complications
11/2020
1Vascular Remodeling
11/2020
1Aortic Valve Stenosis (Aortic Stenosis)
01/2018
1Thoracic Aortic Aneurysm
01/2018
1Psychotic Disorders (Schizoaffective Disorder)
01/2018
1Body Weight (Weight, Body)
01/2018
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2017
1Mental Disorders (Mental Disorder)
01/2015
1Inflammation (Inflammations)
06/2014
1Pulmonary Arterial Hypertension
05/2013
1Edema (Dropsy)
06/2012
1Prostatic Neoplasms (Prostate Cancer)
09/2010
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
09/2010

Drug/Important Bio-Agent (IBA)

4Calcium-Binding ProteinsIBA
01/2017 - 02/2012
3AntioxidantsIBA
01/2022 - 01/2002
3MicroRNAs (MicroRNA)IBA
01/2021 - 01/2015
3Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2015
3salicylhydroxamic acid (SHAM)IBA
01/2021 - 02/2005
3Receptor for Advanced Glycation End ProductsIBA
11/2020 - 02/2012
3CytokinesIBA
10/2008 - 01/2002
3omapatrilatIBA
10/2005 - 12/2003
3Vasopeptidase InhibitorsIBA
10/2005 - 12/2003
2Olanzapine (Zyprexa)FDA Link
01/2022 - 01/2018
2Antipsychotic Agents (Antipsychotics)IBA
01/2022 - 01/2018
2Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2014
2LigandsIBA
11/2020 - 02/2012
2Caspase 3 (Caspase-3)IBA
01/2018 - 07/2014
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2015 - 03/2010
2Protein Isoforms (Isoforms)IBA
06/2014 - 03/2010
2Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2014 - 03/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2014 - 05/2013
2Angiotensin Receptor AntagonistsIBA
11/2005 - 04/2005
2Insulin (Novolin)FDA Link
11/2005 - 10/2005
2Losartan (Cozaar)FDA LinkGeneric
11/2005 - 04/2005
2Probucol (Lorelco)FDA Link
05/2002 - 01/2002
1LipopolysaccharidesIBA
10/2022
1Protein Deglycase DJ-1IBA
01/2022
13' Untranslated Regions (3' UTR)IBA
01/2022
1Messenger RNA (mRNA)IBA
01/2022
1Oncogene Proteins (Oncogene Protein)IBA
06/2021
1Pathogen-Associated Molecular Pattern MoleculesIBA
01/2021
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2021
1Pattern Recognition ReceptorsIBA
01/2021
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2021
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
01/2021
1Metoprolol (Toprol-XL)FDA LinkGeneric
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1OligonucleotidesIBA
01/2018
1Pharmaceutical PreparationsIBA
01/2018
1Streptozocin (Streptozotocin)FDA Link
01/2018
1Fas Ligand Protein (Fas Ligand)IBA
01/2018
1CalciumIBA
01/2017
1CalcineurinIBA
01/2017
1Advanced Glycation End ProductsIBA
07/2014
1Glycoproteins (Glycoprotein)IBA
07/2014
1S100 Proteins (S 100 Protein)IBA
06/2014
1AlarminsIBA
06/2014
1Imatinib Mesylate (Gleevec)FDA Link
05/2013
1InterferonsIBA
05/2013
1MonocrotalineIBA
05/2013
1Interleukin-10 (Interleukin 10)IBA
05/2013
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
05/2013
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
03/2013
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
06/2012
1ResveratrolIBA
06/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
02/2012
1BRCA2 ProteinIBA
02/2012
1MitogensIBA
02/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2012
1DNA (Deoxyribonucleic Acid)IBA
12/2011

Therapy/Procedure

7Ligation
01/2021 - 03/2010
2Punctures
01/2021 - 06/2012
2Therapeutics
01/2021 - 03/2010
1Electric Countershock (Cardioversion)
01/2021
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2018
1Microbubbles
01/2017